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  3. Postdoctoral Fellowships in Sedimentary Ancient DNA – Call for Applications

Postdoctoral Fellowships in Sedimentary Ancient DNA – Call for Applications

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Posted on January 22, 2026
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We are recruiting three full-time Postdoctoral Fellows (PDFs) to join our new NSERC Alliance project. These positions will lead major components of the research program and help build the Canadian Ancient DNA Network.

 

Positions overview 

We invite applications for three full-time Postdoctoral Fellow (PDF) positions associated with a new NSERC Alliance-funded collaboration between the McMaster Ancient DNA Centre and the Hakai Institute (Tula Foundation). These positions will join a coordinated program to improve sedimentary ancient DNA (sedaDNA) methods and reconstruct past ecosystems from terrestrial permafrost and marine sediment archives, while helping to build the Canadian Ancient DNA (Can-aDNA) Network.

Each PDF will lead one of three research streams:

  1. Permafrost sedaDNA (method development and palaeoecological reconstructions)
  2. Marine sedaDNA (method development and palaeoecological reconstructions)
  3. Computational / Bioinformatics (sedaDNA workflows, taxon identification, phylogenetics, palaeoecological modeling)

All three positions will be joint appointments between McMaster University (Hamilton, Ontario, Canada) and the Hakai Institute’s Ancient DNA Lab on Quadra Island, BC (Canada). PDFs will work closely with Dr. Hendrik Poinar (McMaster University) and Dr. Tyler Murchie (Hakai Institute), alongside collaborators Dr. Duane Froese (University of Alberta), Cooper Stacey (Natural Resources Canada), and partner institutions such as the Yukon Government, the University of Victoria, and the University of British Columbia.

Project overview

Our program aims to:

  • Experimentally improve and optimize sedaDNA workflows (extraction/purification, library preparation, capture enrichment, and metagenomic analysis) for terrestrial permafrost and marine sediments.
  • Use these improved methods to reconstruct long-term terrestrial and marine ecosystem dynamics across the Quaternary, focusing on Canadian relic permafrost deposits and Pacific marine cores around Vancouver Island and the Canadian Arctic.
  • Build the Canadian Ancient DNA (Can-aDNA) Network, a national platform for methodological sharing, training, and coordinated method comparisons and validation across Canadian ancient DNA labs.

Position 1: Permafrost sedaDNA Postdoctoral Fellow

Focus
Metagenomic analyses of terrestrial permafrost cores from the Yukon, Alaska, and other regions of northern Canada, using sedaDNA to reconstruct Quaternary ecosystems and test methodological optimizations for DNA recovery and authentication.

Example activities

  • Work with permafrost cores from Canadian permafrost archives, including subsampling, DNA extraction, library preparation, and capture enrichment under strict ancient DNA protocols.
  • Optimize workflows for DNA release from organo-mineral complexes, inhibitor removal, and library preparation efficiencies for highly degraded, low-abundance DNA.
  • Apply and refine targeted capture approaches for plants, vertebrates, and other taxa to reconstruct past ecosystems and ecological transitions, including building in-house baits.
  • Integrate sedaDNA results with stratigraphic, geochronologic, and palaeoenvironmental data to address questions about biodiversity change, extinction, and adaptation through glacial–interglacial cycles.

Apply for the permafrost sedaDNA position here.

Position 2: Marine sedaDNA Postdoctoral Fellow

Focus
Marine sediment cores from Barkley Canyon (deep sea) and Saanich Inlet (nearshore, varved sediments), among other sites with available cores (such as Howe Sound and seamounts in Queen Charlotte Sound), to reconstruct long- and short-term marine biodiversity and food-web dynamics, and to develop improved marine sedaDNA protocols.

Example activities

  • Lead sedaDNA work on archived cores from the Institute for Ocean Sciences and related repositories, spanning the late Pleistocene and Holocene.
  • Combine DNA metabarcoding, ddPCR, and hybridization capture to track changes in plankton, macrophytes, and fish communities through time.
  • Link sedaDNA signals to known oceanographic records (e.g., productivity, oxygenation, carbon cycling) and physical core stratigraphy.
  • Help benchmark and refine marine sedaDNA workflows for broader use in palaeo-oceanography and conservation applications.

Apply for the marine sedaDNA position here.

Position 3: Computational / Bioinformatics Postdoctoral Fellow

Focus
Cross-cutting analytics and method development across permafrost and marine components, with an emphasis on metagenomics, de novo assembly, classification accuracy, and reproducible and sensitive pipelines. Develop AI or machine learning classification tools for low read abundance data and model the accuracy and robustness of palaeoecological reconstructions (using serially sampled, temporally discrete isolates).

Example activities

  • Test and optimize pipelines for shotgun, capture-enriched, and metabarcoding sedaDNA data, including quality control, taxonomic assignment, phylogenetics, and community analyses.
  • Evaluate and compare metagenomic classifiers using simulated and empirical data to quantify false-positive and false-negative rates.
  • Explore machine-learning approaches for improved sedaDNA identification and ecological dynamics reconstructions.
  • Work with McMaster and Hakai’s in-house high-performance computing systems and bioinformatics teams to support the project’s analytical needs.

Apply for the bioinformatics position here.

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Responsibilities (all positions)

Postdoctoral Fellows will:

  • Lead an independent but collaborative research program within their thematic area (permafrost, marine, or bioinformatics), including experimental design, data generation, analysis, and manuscript preparation.
  • Mentor and collaborate with PhD candidates and other trainees working on related sedaDNA projects (1–2 PhD and/or MSc students).
  • Contribute to the Can-aDNA Network, including organizing and moderating online seminars, helping coordinate annual symposia, and engaging with the national community through the online forum.
  • Spend time at both the Hakai Institute Biodiversity Genomics facilities on Quadra Island, BC (near Campbell River, Vancouver Island) and McMaster University (Hamilton, Ontario), and at other collaborating institutions as needed. On-site accommodations are available for researchers at Hakai.
  • Present research at national and international conferences and contribute to open, reproducible data and method sharing.

 

Qualifications

Required (all positions)

  • PhD (completed or near completion) in a relevant field such as ancient DNA, molecular ecology, biomolecular archaeology, evolutionary genomics, bioinformatics, marine science, Quaternary science, or a related discipline.
  • Demonstrated experience with ancient or environmental DNA and/or high-throughput sequencing data, with contamination control for the wet-lab-heavy roles, or with large-scale sequence data analysis and pipelines for the bioinformatics role.
  • Strong quantitative, analytical, and writing skills, with evidence of peer-reviewed publications commensurate with career stage.
  • Ability to work collaboratively within a multi-institution, interdisciplinary team and to mentor junior trainees.

Preferred, position-specific

  • Permafrost PDF: Experience with permafrost, Quaternary geology, palaeoecology, or sedimentary archives; prior work with sedaDNA or ancient DNA strongly preferred.
  • Marine PDF: Background in marine ecology, oceanography, marine genomics, or sedimentary records; familiarity with metabarcoding, ddPCR, or marine monitoring data is an asset.
  • Bioinformatics PDF: Strong skills in programming (e.g., Python, R, Bash, machine learning), high-performance computing, and metagenomic analysis; prior work with classifier benchmarking or machine-learning approaches is an advantage.

We are committed to building an inclusive research environment and strongly encourage applications from members of equity-deserving and historically underrepresented groups.

Terms and compensation

  • Appointment length: 2 years (with the possibility of extension subject to funding and performance, in accordance with institutional policies).
  • Annual salary: CAD $70,000 plus benefits, provided in accordance with McMaster University guidelines.
  • Postdoctoral fellows will be employees of McMaster University, working closely with and spending time at the Hakai Institute.
  • Normal hours of work are 35 hours per week.

How to apply

Please submit the following as a single PDF file through McMaster’s MOSAIC system (links with descriptions above):

  1. Cover letter (1–2 pages) describing:
    • Which position(s) you are applying for (Permafrost, Marine, Bioinformatics; you may indicate more than one in order of preference).
    • How your previous experience fits the project(s) and your research interests.
    • Your earliest possible start date and any constraints.
  2. Curriculum vitae (including full publication list).
  3. Contact information for 2–3 referees (no letters required at the initial stage).

Review of applications will begin on February 24, 2026 and continue until the positions are filled.

For more information

Informal inquiries about the positions or the Alliance project are welcome and can be directed to:

  • Dr. Hendrik Poinar, McMaster Ancient DNA Centre <poinarh@mcmaster.ca>
  • Dr. Tyler Murchie, Hakai Institute / McMaster University <tyler.murchie@hakai.org>

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