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McMaster Ancient DNA News

Second-Pandemic Strain of Vibrio cholerae from the Philadelphia Cholera Outbreak of 1849

Research paper on the identification and retrieval of Vibrio cholerae from preserved intestines of a victim of the 1849 cholera outbreak in Philadelphia, part of the second cholera pandemic.

Feb 05, 2014

Genomics: Plague's progress

Nature news article on the first complete sequence of Yersinia pestis, the causative agent of the Black Death.

Oct 26, 2011

Plague genome: The Black Death decoded

Nature News article on the first plague genome.

Oct 26, 2011

Scientists Solve DNA Puzzle of the Black Death

Press stories surrounding the McMaster Ancient DNA Centre's recent work on the completion of the Yersinia pestis's (plague genome).

Oct 12, 2011

A draft genome of Yersinia pestis from victims of the Black Death

This paper reports the first complete genome of the causitive agent behind the Black Death, Yersinia pestis. Notably it also shows that modern Yersinia pestis strains have stem from these medieval lineages and suggest that factors other than bacterial phenotype may have played a large role in the increased virulance of the Black Death strain.

Oct 12, 2011

Researchers Find Antibiotic Resistance in Ancient DNA

The New York Times article on recent work by the McMaster Ancient DNA Centre on the discovery of antibiotic resistance genes in 30,000-year-old Yukon sediment.

Sep 01, 2011

Antibiotic resistance is ancient

This work illustrates that antibiotic resistance is a naturally occurring, widespread phenomenon that predates our extensive use of antibiotics. This is consistent with the rapid rise of antibiotic resistance in clinical settings which likely build on establish antibiotic resistance genes in their environments.

Sep 01, 2011

Sequencing the Microbe that Causes Bubonic Plague

The New York Times's article on the work of researchers from the McMaster Ancient DNA Centre and its collaborators on the identification of the microbe responsible for the Black Death.

Aug 30, 2011

Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death

Here we report the entire full pPCP1 virulence-associated plasmid of Yersinia pestis as high coverage, the longest contingous genomic sequence of an ancient pathogen to date. Further analysis shows that this plasmid belongs to a Y. pestis strain that has not been previously reported and as such is likely not responsible for modern forms of the disease.

Aug 29, 2011